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Specific MHC-I Peptides Are Induced Using PROTACs

Peptides presented by the class-I major histocompatibility complex (MHC-I) are important targets for immunotherapy. The identification of these peptide targets greatly facilitates the generation of T-cell-based therapeutics. Herein, we report the capability of proteolysis targeting chimera (PROTAC)...

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Detalles Bibliográficos
Autores principales:	Jensen, Stephanie M., Potts, Gregory K., Ready, Damien B., Patterson, Melanie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262898/ https://www.ncbi.nlm.nih.gov/pubmed/30524438 http://dx.doi.org/10.3389/fimmu.2018.02697

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