Cargando…

Genomic insights into virulence mechanisms of Leishmania donovani: evidence from an atypical strain

BACKGROUND: Leishmaniasis is a neglected tropical disease with diverse clinical phenotypes, determined by parasite, host and vector interactions. Despite the advances in molecular biology and the availability of more Leishmania genome references in recent years, the association between parasite spec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Samarasinghe, Sumudu R., Samaranayake, Nilakshi, Kariyawasam, Udeshika L., Siriwardana, Yamuna D., Imamura, Hideo, Karunaweera, Nadira D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262978/ https://www.ncbi.nlm.nih.gov/pubmed/30486770 http://dx.doi.org/10.1186/s12864-018-5271-z

Ejemplares similares

Leishmania donovani Induced Cutaneous Leishmaniasis: An Insight into Atypical Clinical Variants in Sri Lanka
por: Siriwardana, Yamuna, et al.
Publicado: (2019)

Cytokine and phenotypic cell profiles in human cutaneous leishmaniasis caused by Leishmania donovani
por: Wijesooriya, Hiruni, et al.
Publicado: (2023)

Diagnostic Tools for Cutaneous Leishmaniasis Caused by Leishmania donovani: A Narrative Review
por: Piyasiri, Sachee Bhanu, et al.
Publicado: (2023)

Evidence for Seroprevalence in Human Localized Cutaneous Leishmaniasis Caused by Leishmania donovani in Sri Lanka
por: Siriwardana, Yamuna Deepani, et al.
Publicado: (2018)

Leishmania donovani and Cutaneous Leishmaniasis, Sri Lanka
por: Siriwardana, H. V. Yamuna D., et al.
Publicado: (2007)

Genetic diversity of Leishmania donovani that causes cutaneous leishmaniasis in Sri Lanka: a cross sectional study with regional comparisons
por: Kariyawasam, Udeshika Lakmini, et al.
Publicado: (2017)

Trends in Recently Emerged Leishmania donovani Induced Cutaneous Leishmaniasis, Sri Lanka, for the First 13 Years
por: Siriwardana, Yamuna, et al.
Publicado: (2019)

First Serological Study Revealing High Humoral Response and Evidence for Antigenic Heterogeneity in Leishmania donovani Induced CL in Sri Lanka
por: Deepachandi, Bhagya, et al.
Publicado: (2020)

Dermotropic Leishmania donovani in Sri Lanka: visceralizing potential in clinical and preclinical studies
por: KARIYAWASAM, K. K. G. D. U. L., et al.
Publicado: (2018)

Spatial Epidemiologic Trends and Hotspots of Leishmaniasis, Sri Lanka, 2001–2018
por: Karunaweera, Nadira D., et al.
Publicado: (2020)

First Evidence from Sri Lanka for Subphenotypic Diversity within L. donovani-Induced Classical Cutaneous Leishmaniasis
por: Siriwardana, Yamuna, et al.
Publicado: (2021)

Quantification of Soluble or Insoluble Fractions of Leishmania Parasite Proteins in Microvolume Applications: A Simplification to Standard Lowry Assay
por: Deepachandi, Bhagya, et al.
Publicado: (2020)

Genetic diversity and population structure of Phlebotomus argentipes: Vector of Leishmania donovani in Sri Lanka
por: Pathirage, Dulani Ruwanika K., et al.
Publicado: (2021)

A highly sensitive modified nested PCR to enhance case detection in leishmaniasis
por: Deepachandi, Bhagya, et al.
Publicado: (2019)

Prevalidation of an ELISA for Detection of a New Clinical Entity: Leishmania donovani-Induced Cutaneous Leishmaniasis
por: Deepachandi, Bhagya, et al.
Publicado: (2020)

Loop-mediated isothermal amplification assay as a sensitive diagnostic tool for Leishmania donovani infections in Sri Lanka
por: Kothalawala, H S, et al.
Publicado: (2016)

New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence
por: Melo, Guilherme D., et al.
Publicado: (2017)

Identification of internalin-A-like virulent proteins in Leishmania donovani
por: Mukherjee, Ishita, et al.
Publicado: (2016)

Association of HLA class I and II genes with cutaneous leishmaniasis: a case control study from Sri Lanka and a systematic review
por: Samaranayake, Nilakshi, et al.
Publicado: (2016)

Genomic and Metabolomic Polymorphism among Experimentally Selected Paromomycin-Resistant Leishmania donovani Strains
por: Shaw, C. D., et al.
Publicado: (2019)

Global genome diversity of the Leishmania donovani complex
por: Franssen, Susanne U, et al.
Publicado: (2020)

High throughput single-cell genome sequencing gives insights into the generation and evolution of mosaic aneuploidy in Leishmania donovani
por: Negreira, Gabriel H, et al.
Publicado: (2021)

Linking In Vitro and In Vivo Survival of Clinical Leishmania donovani Strains
por: Vanaerschot, Manu, et al.
Publicado: (2010)

Molecular Preadaptation to Antimony Resistance in Leishmania donovani on the Indian Subcontinent
por: Dumetz, F., et al.
Publicado: (2018)

LEISHMANIA DONOVANI IN THE PERIPHERAL BLOOD
por: Young, Charles W., et al.
Publicado: (1923)

Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs
por: Rastrojo, Alberto, et al.
Publicado: (2018)

Leishmania donovani Infection with Atypical Cutaneous Manifestations, Himachal Pradesh, India, 2014–2018
por: Thakur, Lovlesh, et al.
Publicado: (2020)

Integrative genomic, proteomic and phenotypic studies of Leishmania donovani strains revealed genetic features associated with virulence and antimony-resistance
por: Zheng, Zhiwan, et al.
Publicado: (2020)

Single locus genotyping to track Leishmania donovani in the Indian subcontinent: Application in Nepal
por: Rai, Keshav, et al.
Publicado: (2017)

Polymorphism in the HASPB Repeat Region of East African Leishmania donovani Strains
por: Zackay, Arie, et al.
Publicado: (2013)

An Insight Into Systemic Immune Response in Leishmania donovani Mediated Atypical Cutaneous Leishmaniasis in the New Endemic State of Himachal Pradesh, India
por: Thakur, Lovlesh, et al.
Publicado: (2022)

Proteomic analysis of the secretome of Leishmania donovani
por: Silverman, J Maxwell, et al.
Publicado: (2008)

Surface antigens of Leishmania donovani promastigotes
Publicado: (1983)

Vaccine Development Against Leishmania donovani
por: Das, Amrita, et al.
Publicado: (2012)

Leishmania donovani bodies in bone marrow
por: Ali, Natasha, et al.
Publicado: (2014)

An intraspecies Leishmania donovani hybrid from the Indian subcontinent is associated with an atypical phenotype of cutaneous disease
por: Lypaczewski, Patrick, et al.
Publicado: (2022)

A complete Leishmania donovani reference genome identifies novel genetic variations associated with virulence
por: Lypaczewski, Patrick, et al.
Publicado: (2018)

Genomic Analysis of Colombian Leishmania panamensis strains with different level of virulence
por: Urrea, Daniel Alfonso, et al.
Publicado: (2018)

Complete assembly of the Leishmania donovani (HU3 strain) genome and transcriptome annotation
por: Camacho, Esther, et al.
Publicado: (2019)

Insights from the analysis of a predicted model of gp63 in Leishmania donovani
por: Razzazan, Ali, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_4ldukl82na43mginr1q1140gik