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Tissue engineering for the repair of peripheral nerve injury

Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biolog...

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Autores principales: Zhang, Pei-Xun, Han, Na, Kou, Yu-Hui, Zhu, Qing-Tang, Liu, Xiao-Lin, Quan, Da-Ping, Chen, Jian-Guo, Jiang, Bao-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263012/
https://www.ncbi.nlm.nih.gov/pubmed/30531070
http://dx.doi.org/10.4103/1673-5374.243701
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author Zhang, Pei-Xun
Han, Na
Kou, Yu-Hui
Zhu, Qing-Tang
Liu, Xiao-Lin
Quan, Da-Ping
Chen, Jian-Guo
Jiang, Bao-Guo
author_facet Zhang, Pei-Xun
Han, Na
Kou, Yu-Hui
Zhu, Qing-Tang
Liu, Xiao-Lin
Quan, Da-Ping
Chen, Jian-Guo
Jiang, Bao-Guo
author_sort Zhang, Pei-Xun
collection PubMed
description Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold material, the seed cells and various growth factors. Understanding the type of nerve injury, the construction of scaffold and the process of repair are necessary to solve peripheral nerve injury and promote its regeneration. This review describes the categories of peripheral nerve injury, fundamental research of peripheral nervous tissue engineering and clinical research on peripheral nerve scaffold material, and paves a way for related research and the use of conduits in clinical practice.
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spelling pubmed-62630122019-01-01 Tissue engineering for the repair of peripheral nerve injury Zhang, Pei-Xun Han, Na Kou, Yu-Hui Zhu, Qing-Tang Liu, Xiao-Lin Quan, Da-Ping Chen, Jian-Guo Jiang, Bao-Guo Neural Regen Res Research Article Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold material, the seed cells and various growth factors. Understanding the type of nerve injury, the construction of scaffold and the process of repair are necessary to solve peripheral nerve injury and promote its regeneration. This review describes the categories of peripheral nerve injury, fundamental research of peripheral nervous tissue engineering and clinical research on peripheral nerve scaffold material, and paves a way for related research and the use of conduits in clinical practice. Medknow Publications & Media Pvt Ltd 2019-01 /pmc/articles/PMC6263012/ /pubmed/30531070 http://dx.doi.org/10.4103/1673-5374.243701 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Research Article
Zhang, Pei-Xun
Han, Na
Kou, Yu-Hui
Zhu, Qing-Tang
Liu, Xiao-Lin
Quan, Da-Ping
Chen, Jian-Guo
Jiang, Bao-Guo
Tissue engineering for the repair of peripheral nerve injury
title Tissue engineering for the repair of peripheral nerve injury
title_full Tissue engineering for the repair of peripheral nerve injury
title_fullStr Tissue engineering for the repair of peripheral nerve injury
title_full_unstemmed Tissue engineering for the repair of peripheral nerve injury
title_short Tissue engineering for the repair of peripheral nerve injury
title_sort tissue engineering for the repair of peripheral nerve injury
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263012/
https://www.ncbi.nlm.nih.gov/pubmed/30531070
http://dx.doi.org/10.4103/1673-5374.243701
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