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Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes

BACKGROUND: We demonstrated growing evidence supports a protective role of chlorogenic acid of rat hepatocytes elicited by two compounds, i.e. thapsigargin and palmitic acid. Nevertheless, little is known about the mechanisms of palmitic acid induced endoplasmic reticulum (ER) stress and cell death....

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Miao, Liangsheng, Zhang, Huijuan, Wu, Gang, Zhang, Zhenni, Lv, Jianrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263050/
https://www.ncbi.nlm.nih.gov/pubmed/30486828
http://dx.doi.org/10.1186/s12944-018-0916-0