The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease

BACKGROUND: Diagnosis of systemic autoimmune rheumatic diseases (SARD) relies on the presence of hallmark anti-nuclear antibodies (ANA), many of which can be detected years before clinical manifestations. However, ANAs are also seen in healthy individuals, most of whom will not develop SARD. Here, w...

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Detalles Bibliográficos
Autores principales: Baglaenko, Yuriy, Chang, Nan-Hua, Johnson, Sindhu R., Hafiz, Waleed, Manion, Kieran, Ferri, Dario, Noamani, Babak, Bonilla, Dennisse, Rusta-Sellehy, Sina, Lisnevskaia, Larissa, Silverman, Earl, Bookman, Arthur, Landolt-Marticorena, Carolina, Wither, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263058/
https://www.ncbi.nlm.nih.gov/pubmed/30486869
http://dx.doi.org/10.1186/s13075-018-1752-3

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