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Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer

BACKGROUND: A combination of entinostat, all-trans retinoic acid, and doxorubicin (EAD) induces cell death and differentiation and causes significant regression of xenografts of triple-negative breast cancer (TNBC). METHODS: We investigated the mechanisms underlying the antitumor effects of each com...

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Detalles Bibliográficos
Autores principales:	Merino, Vanessa F., Cho, Soonweng, Nguyen, Nguyen, Sadik, Helen, Narayan, Athira, Talbot, Conover, Cope, Leslie, Zhou, Xian C., Zhang, Zhe, Győrffy, Balázs, Sukumar, Saraswati
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263070/ https://www.ncbi.nlm.nih.gov/pubmed/30486871 http://dx.doi.org/10.1186/s13058-018-1068-x

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