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Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing

Aβ peptides, the major components of Alzheimer’s disease (AD) amyloid deposits, are released following sequential cleavages by secretases of its precursor named the amyloid precursor protein (APP). In addition to secretases, degradation pathways, in particular the endosomal/lysosomal and proteasomal...

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Detalles Bibliográficos
Autores principales:	Evrard, Caroline, Kienlen-Campard, Pascal, Coevoet, Mathilde, Opsomer, Rémi, Tasiaux, Bernadette, Melnyk, Patricia, Octave, Jean-Noël, Buée, Luc, Sergeant, Nicolas, Vingtdeux, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263093/ https://www.ncbi.nlm.nih.gov/pubmed/30524243 http://dx.doi.org/10.3389/fncel.2018.00435

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