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Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

In view of the multifactorial nature of Alzheimer’s disease (AD), multitarget small molecules (MTSM) represent the most potent and attractive therapeutic strategy to design new drugs for Alzheimer’s disease therapy. The new MTSM KojoTacrines (KTs) were designed and synthesized by juxtaposition of se...

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Detalles Bibliográficos
Autores principales: Dgachi, Youssef, Martin, Hélène, Malek, Rim, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Iriepa, Isabel, Moraleda, Ignacio, Maalej, Emna, Carreiras, M. Carmo, Refouvelet, Bernard, Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263107/
https://www.ncbi.nlm.nih.gov/pubmed/30482062
http://dx.doi.org/10.1080/14756366.2018.1538136