Synthesis and biological evaluation of benzothiazin-4-ones: a possible new class of acetylcholinesterase inhibitors

A series of nineteen benzothiazin-4-ones from N-(3-aminopropyl) piperidine, 4-(2-aminoethyl)morpholine or 1-(2-aminoethyl)piperidine, aliphatic or aromatic aldehyde and thiosalicylic acid, were synthesized in good yields by multicomponent one-pot reactions. The solvent was toluene and this efficient...

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Detalles Bibliográficos
Autores principales: Berwaldt, Gabriele A., Gouvêa, Daniela P., da Silva, Daniel S., das Neves, Adriana M., Soares, Mayara S. P., Azambuja, Juliana H., Siqueira, Geonir M., Spanevello, Roselia M., Cunico, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263113/
https://www.ncbi.nlm.nih.gov/pubmed/30482059
http://dx.doi.org/10.1080/14756366.2018.1543286

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