Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia

Lung-innervating nociceptor sensory neurons detect noxious or harmful stimuli and consequently protect organisms by mediating coughing, pain, and bronchoconstriction. However, the role of sensory neurons in pulmonary host defense is unclear. Here, we found that TRPV1(+) nociceptors suppressed protec...

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Detalles Bibliográficos
Autores principales: Baral, Pankaj, Umans, Benjamin D, Li, Lu, Wallrapp, Antonia, Bist, Meghna, Kirschbaum, Talia, Wei, Yibing, Zhou, Yan, Kuchroo, Vijay K, Burkett, Patrick R, Yipp, Bryan G, Liberles, Stephen D, Chiu, Isaac M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263165/
https://www.ncbi.nlm.nih.gov/pubmed/29505031
http://dx.doi.org/10.1038/nm.4501

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