Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates

Oligo(ε-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and co...

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Autores principales: Sobczak, Marcin, Nurzyńska, Katarzyna, Kolodziejski, Waclaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263196/
https://www.ncbi.nlm.nih.gov/pubmed/20335951
http://dx.doi.org/10.3390/molecules15020842
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author Sobczak, Marcin
Nurzyńska, Katarzyna
Kolodziejski, Waclaw
author_facet Sobczak, Marcin
Nurzyńska, Katarzyna
Kolodziejski, Waclaw
author_sort Sobczak, Marcin
collection PubMed
description Oligo(ε-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and conjugates were elucidated by means of MALDI-TOF MS, NMR and IR studies.
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spelling pubmed-62631962018-12-03 Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates Sobczak, Marcin Nurzyńska, Katarzyna Kolodziejski, Waclaw Molecules Article Oligo(ε-caprolactone) and oligolactide were synthesized via ring-opening polymerization of cyclic esters in the presence of creatinine as initiators. Thus obtained oligomers were successfully used in the synthesis of novel polyurethane conjugates of norfloxacin. The structures of the polymers and conjugates were elucidated by means of MALDI-TOF MS, NMR and IR studies. Molecular Diversity Preservation International 2010-02-05 /pmc/articles/PMC6263196/ /pubmed/20335951 http://dx.doi.org/10.3390/molecules15020842 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Sobczak, Marcin
Nurzyńska, Katarzyna
Kolodziejski, Waclaw
Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
title Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
title_full Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
title_fullStr Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
title_full_unstemmed Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
title_short Seeking Polymeric Prodrugs of Norfloxacin. Part 2. Synthesis and Structural Analysis of Polyurethane Conjugates
title_sort seeking polymeric prodrugs of norfloxacin. part 2. synthesis and structural analysis of polyurethane conjugates
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263196/
https://www.ncbi.nlm.nih.gov/pubmed/20335951
http://dx.doi.org/10.3390/molecules15020842
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AT kolodziejskiwaclaw seekingpolymericprodrugsofnorfloxacinpart2synthesisandstructuralanalysisofpolyurethaneconjugates

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