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Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire

PURPOSE: The aim of this study was to evaluate the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire and to determine the clinical variables that are related to CDLM scores. METHODS: This was an observational, cross-sectional, and multicent...

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Autores principales: Núñez, Alexa, Esquinas, Cristina, Barrecheguren, Miriam, Calle, Myriam, Casamor, Ricard, Miravitlles, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263249/
https://www.ncbi.nlm.nih.gov/pubmed/30538445
http://dx.doi.org/10.2147/COPD.S179402
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author Núñez, Alexa
Esquinas, Cristina
Barrecheguren, Miriam
Calle, Myriam
Casamor, Ricard
Miravitlles, Marc
author_facet Núñez, Alexa
Esquinas, Cristina
Barrecheguren, Miriam
Calle, Myriam
Casamor, Ricard
Miravitlles, Marc
author_sort Núñez, Alexa
collection PubMed
description PURPOSE: The aim of this study was to evaluate the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire and to determine the clinical variables that are related to CDLM scores. METHODS: This was an observational, cross-sectional, and multicenter study conducted in stable COPD patients. CDLM scores ranged from 0 to 5 and were transformed into a qualitative variable according to tertile values to compare patient characteristics. A multivariate linear regression model was used to identify the clinical variables related to CDLM scores. RESULTS: A total of 605 patients were included in the study; the mean age (SD) was 68 years (9.1) and mostly were male (80.8%). The mean post-bronchodilator FEV(1)% was 53.4% (19.2%), and the mean BODEx (body mass index, airway obstruction, dyspnea, exacerbation) score was 3.2 (2.0). The mean COPD assessment test (CAT) score was 16.6 (8.3), and the mean CDLM score was 4.2 (0.9). First tertile patients, that is, those with a higher impact in the morning, were older, had more respiratory symptoms, more dyspnea, a lower FEV(1)%, lower CAT and BODEx scores, and more exacerbations. We found a ceiling effect on the CDLM scores: 194 (32%) patients scored 5.00 and no patients scored 0. On multivariate analysis, higher CAT and BODEx scores, a lower FEV(1)%, and use of long-term oxygen therapy (LTOT) were all independently related to lower CDLM scores. CONCLUSION: Morning respiratory symptoms are associated with more severe airflow obstruction, lower CAT and BODEx scores, and LTOT. The ceiling effect of the CDLM questionnaire does not allow it to discriminate well between low and high impact of morning symptoms.
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spelling pubmed-62632492018-12-11 Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire Núñez, Alexa Esquinas, Cristina Barrecheguren, Miriam Calle, Myriam Casamor, Ricard Miravitlles, Marc Int J Chron Obstruct Pulmon Dis Original Research PURPOSE: The aim of this study was to evaluate the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire and to determine the clinical variables that are related to CDLM scores. METHODS: This was an observational, cross-sectional, and multicenter study conducted in stable COPD patients. CDLM scores ranged from 0 to 5 and were transformed into a qualitative variable according to tertile values to compare patient characteristics. A multivariate linear regression model was used to identify the clinical variables related to CDLM scores. RESULTS: A total of 605 patients were included in the study; the mean age (SD) was 68 years (9.1) and mostly were male (80.8%). The mean post-bronchodilator FEV(1)% was 53.4% (19.2%), and the mean BODEx (body mass index, airway obstruction, dyspnea, exacerbation) score was 3.2 (2.0). The mean COPD assessment test (CAT) score was 16.6 (8.3), and the mean CDLM score was 4.2 (0.9). First tertile patients, that is, those with a higher impact in the morning, were older, had more respiratory symptoms, more dyspnea, a lower FEV(1)%, lower CAT and BODEx scores, and more exacerbations. We found a ceiling effect on the CDLM scores: 194 (32%) patients scored 5.00 and no patients scored 0. On multivariate analysis, higher CAT and BODEx scores, a lower FEV(1)%, and use of long-term oxygen therapy (LTOT) were all independently related to lower CDLM scores. CONCLUSION: Morning respiratory symptoms are associated with more severe airflow obstruction, lower CAT and BODEx scores, and LTOT. The ceiling effect of the CDLM questionnaire does not allow it to discriminate well between low and high impact of morning symptoms. Dove Medical Press 2018-11-26 /pmc/articles/PMC6263249/ /pubmed/30538445 http://dx.doi.org/10.2147/COPD.S179402 Text en © 2018 Núñez et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Núñez, Alexa
Esquinas, Cristina
Barrecheguren, Miriam
Calle, Myriam
Casamor, Ricard
Miravitlles, Marc
Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
title Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
title_full Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
title_fullStr Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
title_full_unstemmed Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
title_short Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
title_sort evaluating the impact of morning symptoms in copd using the capacity of daily living during the morning (cdlm) questionnaire
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263249/
https://www.ncbi.nlm.nih.gov/pubmed/30538445
http://dx.doi.org/10.2147/COPD.S179402
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