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Mangiferin, an Anti-HIV-1 Agent Targeting Protease and Effective against Resistant Strains
The anti-HIV-1 activity of mangiferin was evaluated. Mangiferin can inhibit HIV-1(ⅢB) induced syncytium formation at non-cytotoxic concentrations, with a 50% effective concentration (EC(50)) at 16.90 μM and a therapeutic index (TI) above 140. Mangiferin also showed good activities in other laborator...
Autores principales: | Wang, Rui-Rui, Gao, Yue-Dong, Ma, Chun-Hui, Zhang, Xing-Jie, Huang, Cheng-Gang, Huang, Jing-Fei, Zheng, Yong-Tang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263262/ https://www.ncbi.nlm.nih.gov/pubmed/21610656 http://dx.doi.org/10.3390/molecules16054264 |
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