RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions

RuCl(3)·3H(2)O was found to be an effective catalyst for reactions of indoles, 2-methylthiophene, and 2-methylfuran with aldehydes to afford the corresponding bis(indolyl)methanes, bis(thienyl)methanes, and bis(fur-2-yl)methanes in moderate to excellent yields. Experimental results indicated that mo...

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Detalles Bibliográficos
Autores principales: Qu, Hong-En, Xiao, Chen, Wang, Ning, Yu, Kai-Hui, Hu, Qiao-Sheng, Liu, Liang-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263275/
https://www.ncbi.nlm.nih.gov/pubmed/21555975
http://dx.doi.org/10.3390/molecules16053855
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author Qu, Hong-En
Xiao, Chen
Wang, Ning
Yu, Kai-Hui
Hu, Qiao-Sheng
Liu, Liang-Xian
author_facet Qu, Hong-En
Xiao, Chen
Wang, Ning
Yu, Kai-Hui
Hu, Qiao-Sheng
Liu, Liang-Xian
author_sort Qu, Hong-En
collection PubMed
description RuCl(3)·3H(2)O was found to be an effective catalyst for reactions of indoles, 2-methylthiophene, and 2-methylfuran with aldehydes to afford the corresponding bis(indolyl)methanes, bis(thienyl)methanes, and bis(fur-2-yl)methanes in moderate to excellent yields. Experimental results indicated that mono(indolyl)methanol is not the reaction intermediate under these reaction conditions.
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spelling pubmed-62632752018-12-10 RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions Qu, Hong-En Xiao, Chen Wang, Ning Yu, Kai-Hui Hu, Qiao-Sheng Liu, Liang-Xian Molecules Article RuCl(3)·3H(2)O was found to be an effective catalyst for reactions of indoles, 2-methylthiophene, and 2-methylfuran with aldehydes to afford the corresponding bis(indolyl)methanes, bis(thienyl)methanes, and bis(fur-2-yl)methanes in moderate to excellent yields. Experimental results indicated that mono(indolyl)methanol is not the reaction intermediate under these reaction conditions. MDPI 2011-05-09 /pmc/articles/PMC6263275/ /pubmed/21555975 http://dx.doi.org/10.3390/molecules16053855 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Qu, Hong-En
Xiao, Chen
Wang, Ning
Yu, Kai-Hui
Hu, Qiao-Sheng
Liu, Liang-Xian
RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions
title RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions
title_full RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions
title_fullStr RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions
title_full_unstemmed RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions
title_short RuCl(3)·3H(2)O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions
title_sort rucl(3)·3h(2)o catalyzed reactions: facile synthesis of bis(indolyl)methanes under mild conditions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263275/
https://www.ncbi.nlm.nih.gov/pubmed/21555975
http://dx.doi.org/10.3390/molecules16053855
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