Cargando…

Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide

Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N‑iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.

Detalles Bibliográficos
Autores principales: Bagley, Mark C., Glover, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263277/
https://www.ncbi.nlm.nih.gov/pubmed/20657473
http://dx.doi.org/10.3390/molecules15053211
Descripción
Sumario:Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N‑iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.