Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide

Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N‑iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.

Detalles Bibliográficos
Autores principales: Bagley, Mark C., Glover, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263277/
https://www.ncbi.nlm.nih.gov/pubmed/20657473
http://dx.doi.org/10.3390/molecules15053211
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author Bagley, Mark C.
Glover, Christian
author_facet Bagley, Mark C.
Glover, Christian
author_sort Bagley, Mark C.
collection PubMed
description Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N‑iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol.
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spelling pubmed-62632772019-01-02 Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide Bagley, Mark C. Glover, Christian Molecules Article Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N‑iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regiocontrol. MDPI 2010-04-30 /pmc/articles/PMC6263277/ /pubmed/20657473 http://dx.doi.org/10.3390/molecules15053211 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Bagley, Mark C.
Glover, Christian
Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
title Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
title_full Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
title_fullStr Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
title_full_unstemmed Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
title_short Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
title_sort bohlmann-rahtz cyclodehydration of aminodienones to pyridines using n-iodosuccinimide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263277/
https://www.ncbi.nlm.nih.gov/pubmed/20657473
http://dx.doi.org/10.3390/molecules15053211
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