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Apigenin Isolated from the Medicinal Plant Elsholtzia rugulosa Prevents β-Amyloid 25–35-Induces Toxicity in Rat Cerebral Microvascular Endothelial Cells

Endothelial cells of cerebral capillaries forming the blood-brain barrier play an important role in the pathogenesis and therapy of Alzheimer’s disease. Amyloid-β peptides are key pathological elements in the development of this disease. Apigenin (4’,5,7-tetrahydroxyflavone) is a plant flavonoid and...

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Detalles Bibliográficos
Autores principales: Zhao, Le, Hou, Lin, Sun, Huijun, Yan, Xin, Sun, Xifeng, Li, Jianguang, Bian, Yong, Chu, Yu, Liu, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263293/
http://dx.doi.org/10.3390/molecules16054005