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Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study

OBJECTIVES: To determine the incidence and factors associated with median neuropathy at the wrist (MNW) in systemic sclerosis (SSc) patients using an electrodiagnostic (EDX) study. MATERIAL AND METHODS: SSc patients who attended the scleroderma clinic, Srinagarind Hospital, were prospectively evalua...

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Autores principales: Sriwong, Pornhathai T., Sirasaporn, Patpiya, Foochareon, Chingching, Srichompoo, Kannikar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263308/
https://www.ncbi.nlm.nih.gov/pubmed/30505011
http://dx.doi.org/10.5114/reum.2018.79500
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author Sriwong, Pornhathai T.
Sirasaporn, Patpiya
Foochareon, Chingching
Srichompoo, Kannikar
author_facet Sriwong, Pornhathai T.
Sirasaporn, Patpiya
Foochareon, Chingching
Srichompoo, Kannikar
author_sort Sriwong, Pornhathai T.
collection PubMed
description OBJECTIVES: To determine the incidence and factors associated with median neuropathy at the wrist (MNW) in systemic sclerosis (SSc) patients using an electrodiagnostic (EDX) study. MATERIAL AND METHODS: SSc patients who attended the scleroderma clinic, Srinagarind Hospital, were prospectively evaluated by questionnaire, physical examination, and EDX study. The questionnaire consisted of the baseline characteristics, type of scleroderma, clinical signs and symptoms associated with scleroderma, and the Boston questionnaire. The physical examinations were the Modified Rodnan Skin Score, motor power grading of bilateral abductor pollicis brevis muscle, and pinprick sensation of median nerve distribution of both hands. Moreover, the EDX study, which was composed of median and ulnar sensory and motor nerve conduction studies of both hands and electromyography of the abductor pollicis brevis muscles, was evaluated at baseline and following two years. RESULTS: Out of 75 systemic sclerosis patients, 50 individuals participated in the study. Diffuse cutaneous type of SSc is the most common type (72%). The common SSc associated symptoms were Raynaud phenomenon, skin tightness and hand deformity. Incidence of MNW was 90 cases per 1000 person-years. Following a two-year interval, the percentages of mild, moderate and severe MNW were 28%, 22% and 6% respectively. Most of those with MNW were still particularly asymptomatic in a mild degree. Moreover, 12 out of 50 patients (24%) had a worse EDX result. There was no statistically significant association between MNW occurrence and studied factors. CONCLUSIONS: MNW commonly has high incidence in SSc patients. Therefore, SSc patients should be followed up in both clinical and EDX studies for MNW screening. SSc patients with asymptomatic MNW might need clinical follow-up for early diagnosis.
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spelling pubmed-62633082018-11-30 Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study Sriwong, Pornhathai T. Sirasaporn, Patpiya Foochareon, Chingching Srichompoo, Kannikar Reumatologia Original Paper OBJECTIVES: To determine the incidence and factors associated with median neuropathy at the wrist (MNW) in systemic sclerosis (SSc) patients using an electrodiagnostic (EDX) study. MATERIAL AND METHODS: SSc patients who attended the scleroderma clinic, Srinagarind Hospital, were prospectively evaluated by questionnaire, physical examination, and EDX study. The questionnaire consisted of the baseline characteristics, type of scleroderma, clinical signs and symptoms associated with scleroderma, and the Boston questionnaire. The physical examinations were the Modified Rodnan Skin Score, motor power grading of bilateral abductor pollicis brevis muscle, and pinprick sensation of median nerve distribution of both hands. Moreover, the EDX study, which was composed of median and ulnar sensory and motor nerve conduction studies of both hands and electromyography of the abductor pollicis brevis muscles, was evaluated at baseline and following two years. RESULTS: Out of 75 systemic sclerosis patients, 50 individuals participated in the study. Diffuse cutaneous type of SSc is the most common type (72%). The common SSc associated symptoms were Raynaud phenomenon, skin tightness and hand deformity. Incidence of MNW was 90 cases per 1000 person-years. Following a two-year interval, the percentages of mild, moderate and severe MNW were 28%, 22% and 6% respectively. Most of those with MNW were still particularly asymptomatic in a mild degree. Moreover, 12 out of 50 patients (24%) had a worse EDX result. There was no statistically significant association between MNW occurrence and studied factors. CONCLUSIONS: MNW commonly has high incidence in SSc patients. Therefore, SSc patients should be followed up in both clinical and EDX studies for MNW screening. SSc patients with asymptomatic MNW might need clinical follow-up for early diagnosis. Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie 2018-10-31 2018 /pmc/articles/PMC6263308/ /pubmed/30505011 http://dx.doi.org/10.5114/reum.2018.79500 Text en Copyright: © 2018 Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji w Warszawie http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Sriwong, Pornhathai T.
Sirasaporn, Patpiya
Foochareon, Chingching
Srichompoo, Kannikar
Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
title Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
title_full Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
title_fullStr Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
title_full_unstemmed Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
title_short Median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
title_sort median neuropathy at the wrist in patients with systemic sclerosis: two-year follow-up study
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263308/
https://www.ncbi.nlm.nih.gov/pubmed/30505011
http://dx.doi.org/10.5114/reum.2018.79500
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