A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols

Treatment of N-bromosuccinimide (NBS) with (carboethoxymethylene) triphenylphosphorane (1) in CH(2)Cl(2) followed by the addition of an alcohol in the presence of manganese dioxide under ultrasonic irradiation constitutes a stereoselective one-pot procedure for the preparation of Z-configured α–brom...

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Detalles Bibliográficos
Autores principales: Karama, Usama, Al-Othman, Zeid, Al-Majid, Abdullah, Almansour, Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263313/
https://www.ncbi.nlm.nih.gov/pubmed/20657477
http://dx.doi.org/10.3390/molecules15053276
Descripción
Sumario:Treatment of N-bromosuccinimide (NBS) with (carboethoxymethylene) triphenylphosphorane (1) in CH(2)Cl(2) followed by the addition of an alcohol in the presence of manganese dioxide under ultrasonic irradiation constitutes a stereoselective one-pot procedure for the preparation of Z-configured α–bromo-α,β-unsaturated esters in good to excellent yield.

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