A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols

Treatment of N-bromosuccinimide (NBS) with (carboethoxymethylene) triphenylphosphorane (1) in CH(2)Cl(2) followed by the addition of an alcohol in the presence of manganese dioxide under ultrasonic irradiation constitutes a stereoselective one-pot procedure for the preparation of Z-configured α–brom...

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Detalles Bibliográficos
Autores principales: Karama, Usama, Al-Othman, Zeid, Al-Majid, Abdullah, Almansour, Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263313/
https://www.ncbi.nlm.nih.gov/pubmed/20657477
http://dx.doi.org/10.3390/molecules15053276
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author Karama, Usama
Al-Othman, Zeid
Al-Majid, Abdullah
Almansour, Abdulrahman
author_facet Karama, Usama
Al-Othman, Zeid
Al-Majid, Abdullah
Almansour, Abdulrahman
author_sort Karama, Usama
collection PubMed
description Treatment of N-bromosuccinimide (NBS) with (carboethoxymethylene) triphenylphosphorane (1) in CH(2)Cl(2) followed by the addition of an alcohol in the presence of manganese dioxide under ultrasonic irradiation constitutes a stereoselective one-pot procedure for the preparation of Z-configured α–bromo-α,β-unsaturated esters in good to excellent yield.
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spelling pubmed-62633132019-01-02 A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols Karama, Usama Al-Othman, Zeid Al-Majid, Abdullah Almansour, Abdulrahman Molecules Article Treatment of N-bromosuccinimide (NBS) with (carboethoxymethylene) triphenylphosphorane (1) in CH(2)Cl(2) followed by the addition of an alcohol in the presence of manganese dioxide under ultrasonic irradiation constitutes a stereoselective one-pot procedure for the preparation of Z-configured α–bromo-α,β-unsaturated esters in good to excellent yield. MDPI 2010-05-04 /pmc/articles/PMC6263313/ /pubmed/20657477 http://dx.doi.org/10.3390/molecules15053276 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Karama, Usama
Al-Othman, Zeid
Al-Majid, Abdullah
Almansour, Abdulrahman
A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols
title A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols
title_full A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols
title_fullStr A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols
title_full_unstemmed A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols
title_short A Facile One-Pot Synthesis of α-Bromo-α,β-unsaturated Esters from Alcohols
title_sort facile one-pot synthesis of α-bromo-α,β-unsaturated esters from alcohols
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263313/
https://www.ncbi.nlm.nih.gov/pubmed/20657477
http://dx.doi.org/10.3390/molecules15053276
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