Diversity-Oriented Synthesis of a Library of Substituted Tetrahydropyrones Using Oxidative Carbon-Hydrogen Bond Activation and Click Chemistry

Eighteen (2RS,6RS)-2-(4-methoxyphenyl)-6-(substituted ethyl)dihydro-2H-pyran-4(3H)ones were synthesized via a DDQ-mediated oxidative carbon-hydrogen bond activation reaction. Fourteen of these tetrahydropyrans were substituted with triazoles readily assembled via azide-alkyne click-chemistry reactio...

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Detalles Bibliográficos
Autores principales: Zaware, Nilesh, LaPorte, Matthew G., Farid, Ramy, Liu, Lei, Wipf, Peter, Floreancig, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263335/
https://www.ncbi.nlm.nih.gov/pubmed/21540794
http://dx.doi.org/10.3390/molecules16053648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263335/
https://www.ncbi.nlm.nih.gov/pubmed/21540794
http://dx.doi.org/10.3390/molecules16053648

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