Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities

In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exh...

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Autores principales: Li, Xiao-Dong, Kang, Shuai-Tao, Li, Guo-Yu, Li, Xian, Wang, Jin-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263338/
https://www.ncbi.nlm.nih.gov/pubmed/21527885
http://dx.doi.org/10.3390/molecules16053580
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author Li, Xiao-Dong
Kang, Shuai-Tao
Li, Guo-Yu
Li, Xian
Wang, Jin-Hui
author_facet Li, Xiao-Dong
Kang, Shuai-Tao
Li, Guo-Yu
Li, Xian
Wang, Jin-Hui
author_sort Li, Xiao-Dong
collection PubMed
description In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.
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spelling pubmed-62633382018-12-10 Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities Li, Xiao-Dong Kang, Shuai-Tao Li, Guo-Yu Li, Xian Wang, Jin-Hui Molecules Article In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities. MDPI 2011-04-28 /pmc/articles/PMC6263338/ /pubmed/21527885 http://dx.doi.org/10.3390/molecules16053580 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Li, Xiao-Dong
Kang, Shuai-Tao
Li, Guo-Yu
Li, Xian
Wang, Jin-Hui
Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities
title Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities
title_full Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities
title_fullStr Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities
title_full_unstemmed Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities
title_short Synthesis of Some Phenylpropanoid Glycosides (PPGs) and Their Acetylcholinesterase/Xanthine Oxidase Inhibitory Activities
title_sort synthesis of some phenylpropanoid glycosides (ppgs) and their acetylcholinesterase/xanthine oxidase inhibitory activities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263338/
https://www.ncbi.nlm.nih.gov/pubmed/21527885
http://dx.doi.org/10.3390/molecules16053580
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