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Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
Aminolevulinic acid (ALA) is an endogenous metabolite normally formed in the mitochondria from succinyl-CoA and glycine. Conjugation of eight ALA molecules yields protoporphyrin IX (PpIX) and finally leads to formation of heme. Conversion of PpIX to its downstream substrates requires the activity of...
Autores principales: | Wachowska, Małgorzata, Muchowicz, Angelika, Firczuk, Małgorzata, Gabrysiak, Magdalena, Winiarska, Magdalena, Wańczyk, Małgorzata, Bojarczuk, Kamil, Golab, Jakub |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263343/ http://dx.doi.org/10.3390/molecules16054140 |
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