Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine

An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared...

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Detalles Bibliográficos
Autores principales: Gengan, Robert M., Pandian, Pitchai, Kumarsamy, Chandraprakash, Mohan, Palathurai S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263347/
https://www.ncbi.nlm.nih.gov/pubmed/20657469
http://dx.doi.org/10.3390/molecules15053171
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author Gengan, Robert M.
Pandian, Pitchai
Kumarsamy, Chandraprakash
Mohan, Palathurai S.
author_facet Gengan, Robert M.
Pandian, Pitchai
Kumarsamy, Chandraprakash
Mohan, Palathurai S.
author_sort Gengan, Robert M.
collection PubMed
description An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods.
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spelling pubmed-62633472019-01-02 Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine Gengan, Robert M. Pandian, Pitchai Kumarsamy, Chandraprakash Mohan, Palathurai S. Molecules Article An efficient synthesis of a methyl derivative of the indoloquinoline alkaloid cryptosanguinolentine based on microwave-assisted reactions is described. The microwave-assisted synthesis of an intermediate 4-hydroxy-2-methylquinoline yielded 86% of the desired product and other intermediates prepared yielded high % of products in shorter reaction times, under optimum conditions, as compared to traditional methods. MDPI 2010-04-29 /pmc/articles/PMC6263347/ /pubmed/20657469 http://dx.doi.org/10.3390/molecules15053171 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Gengan, Robert M.
Pandian, Pitchai
Kumarsamy, Chandraprakash
Mohan, Palathurai S.
Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
title Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
title_full Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
title_fullStr Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
title_full_unstemmed Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
title_short Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
title_sort convenient and efficient microwave-assisted synthesis of a methyl derivative of the fused indoloquinoline alkaloid cryptosanguinolentine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263347/
https://www.ncbi.nlm.nih.gov/pubmed/20657469
http://dx.doi.org/10.3390/molecules15053171
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