Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines

New diarylquinazolines displaying pharmaceutical potential were synthesized in high yields from 4,7-dichloro-2-(2-methylprop-1-enyl)-6-nitroquinazoline by using microwave-promoted regioselective Suzuki-Miyaura cross-coupling reactions.

Detalles Bibliográficos
Autores principales: Kabri, Youssef, Verhaeghe, Pierre, Gellis, Armand, Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263357/
https://www.ncbi.nlm.nih.gov/pubmed/20657457
http://dx.doi.org/10.3390/molecules15052949
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author Kabri, Youssef
Verhaeghe, Pierre
Gellis, Armand
Vanelle, Patrice
author_facet Kabri, Youssef
Verhaeghe, Pierre
Gellis, Armand
Vanelle, Patrice
author_sort Kabri, Youssef
collection PubMed
description New diarylquinazolines displaying pharmaceutical potential were synthesized in high yields from 4,7-dichloro-2-(2-methylprop-1-enyl)-6-nitroquinazoline by using microwave-promoted regioselective Suzuki-Miyaura cross-coupling reactions.
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spelling pubmed-62633572019-01-02 Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines Kabri, Youssef Verhaeghe, Pierre Gellis, Armand Vanelle, Patrice Molecules Article New diarylquinazolines displaying pharmaceutical potential were synthesized in high yields from 4,7-dichloro-2-(2-methylprop-1-enyl)-6-nitroquinazoline by using microwave-promoted regioselective Suzuki-Miyaura cross-coupling reactions. MDPI 2010-04-27 /pmc/articles/PMC6263357/ /pubmed/20657457 http://dx.doi.org/10.3390/molecules15052949 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Kabri, Youssef
Verhaeghe, Pierre
Gellis, Armand
Vanelle, Patrice
Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines
title Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines
title_full Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines
title_fullStr Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines
title_full_unstemmed Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines
title_short Regioselective Suzuki-Miyaura Reaction: Application to the Microwave-promoted Synthesis of 4,7-Diarylquinazolines
title_sort regioselective suzuki-miyaura reaction: application to the microwave-promoted synthesis of 4,7-diarylquinazolines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263357/
https://www.ncbi.nlm.nih.gov/pubmed/20657457
http://dx.doi.org/10.3390/molecules15052949
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