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Accelerated Laboratory Evolution Reveals the Influence of Replication on the GC Skew in Escherichia coli
Most bacterial genomes display contrasting strand asymmetry in a variety of features, such as nucleotide composition and gene orientation, of the two replichores separated by the replication origin and terminus. The cause for the polarization is often attributed to mutations arising from the asymmet...
Autores principales: | Kono, Nobuaki, Tomita, Masaru, Arakawa, Kazuharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263442/ https://www.ncbi.nlm.nih.gov/pubmed/30371772 http://dx.doi.org/10.1093/gbe/evy237 |
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