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In vivo induction of membrane damage by β-amyloid peptide oligomers
Exposure to the β-amyloid peptide (Aβ) is toxic to neurons and other cell types, but the mechanism(s) involved are still unresolved. Synthetic Aβ oligomers can induce ion-permeable pores in synthetic membranes, but whether this ability to damage membranes plays a role in the ability of Aβ oligomers...
Autores principales: | Julien, Carl, Tomberlin, Colson, Roberts, Christine M., Akram, Aumbreen, Stein, Gretchen H., Silverman, Michael A., Link, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263551/ https://www.ncbi.nlm.nih.gov/pubmed/30497524 http://dx.doi.org/10.1186/s40478-018-0634-x |
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