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In vivo induction of membrane damage by β-amyloid peptide oligomers

Exposure to the β-amyloid peptide (Aβ) is toxic to neurons and other cell types, but the mechanism(s) involved are still unresolved. Synthetic Aβ oligomers can induce ion-permeable pores in synthetic membranes, but whether this ability to damage membranes plays a role in the ability of Aβ oligomers...

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Detalles Bibliográficos
Autores principales: Julien, Carl, Tomberlin, Colson, Roberts, Christine M., Akram, Aumbreen, Stein, Gretchen H., Silverman, Michael A., Link, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263551/
https://www.ncbi.nlm.nih.gov/pubmed/30497524
http://dx.doi.org/10.1186/s40478-018-0634-x

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