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Helmsman: fast and efficient mutation signature analysis for massive sequencing datasets
BACKGROUND: The spectrum of somatic single-nucleotide variants in cancer genomes often reflects the signatures of multiple distinct mutational processes, which can provide clinically actionable insights into cancer etiology. Existing software tools for identifying and evaluating these mutational sig...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263557/ https://www.ncbi.nlm.nih.gov/pubmed/30486787 http://dx.doi.org/10.1186/s12864-018-5264-y |