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EGFET-Based Sensors for Bioanalytical Applications: A Review
Since the 1970s, a great deal of attention has been paid to the development of semiconductor-based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low-cost manufacturing for quick biospecific analysis with reusable feat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263563/ https://www.ncbi.nlm.nih.gov/pubmed/30463318 http://dx.doi.org/10.3390/s18114042 |
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author | Pullano, Salvatore Andrea Critello, Costantino Davide Mahbub, Ifana Tasneem, Nishat Tarannum Shamsir, Samira Islam, Syed Kamrul Greco, Marta Fiorillo, Antonino S. |
author_facet | Pullano, Salvatore Andrea Critello, Costantino Davide Mahbub, Ifana Tasneem, Nishat Tarannum Shamsir, Samira Islam, Syed Kamrul Greco, Marta Fiorillo, Antonino S. |
author_sort | Pullano, Salvatore Andrea |
collection | PubMed |
description | Since the 1970s, a great deal of attention has been paid to the development of semiconductor-based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low-cost manufacturing for quick biospecific analysis with reusable features. Commercial biosensors have become highly desirable in the fields of medicine, food, and environmental monitoring as well as military applications, whereas increasing concerns about food safety and health issues have resulted in the introduction of novel legislative standards for these sensors. Numerous devices have been developed for monitoring biological processes such as nucleic acid hybridization, protein–protein interaction, antigen–antibody bonds, and substrate–enzyme reactions, just to name a few. Since the 1980s, scientific interest moved to the development of semiconductor-based devices, which also include integrated front-end electronics, such as the extended-gate field-effect transistor (EGFET) biosensor, one of the first miniaturized chemical sensors. This work is intended to be a review of the state of the art focused on the development of biosensors and chemosensors based on extended-gate field-effect transistor within the field of bioanalytical applications, which will highlight the most recent research reported in the literature. Moreover, a comparison among the diverse EGFET devices will be presented, giving particular attention to the materials and technologies. |
format | Online Article Text |
id | pubmed-6263563 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62635632018-12-12 EGFET-Based Sensors for Bioanalytical Applications: A Review Pullano, Salvatore Andrea Critello, Costantino Davide Mahbub, Ifana Tasneem, Nishat Tarannum Shamsir, Samira Islam, Syed Kamrul Greco, Marta Fiorillo, Antonino S. Sensors (Basel) Review Since the 1970s, a great deal of attention has been paid to the development of semiconductor-based biosensors because of the numerous advantages they offer, including high sensitivity, faster response time, miniaturization, and low-cost manufacturing for quick biospecific analysis with reusable features. Commercial biosensors have become highly desirable in the fields of medicine, food, and environmental monitoring as well as military applications, whereas increasing concerns about food safety and health issues have resulted in the introduction of novel legislative standards for these sensors. Numerous devices have been developed for monitoring biological processes such as nucleic acid hybridization, protein–protein interaction, antigen–antibody bonds, and substrate–enzyme reactions, just to name a few. Since the 1980s, scientific interest moved to the development of semiconductor-based devices, which also include integrated front-end electronics, such as the extended-gate field-effect transistor (EGFET) biosensor, one of the first miniaturized chemical sensors. This work is intended to be a review of the state of the art focused on the development of biosensors and chemosensors based on extended-gate field-effect transistor within the field of bioanalytical applications, which will highlight the most recent research reported in the literature. Moreover, a comparison among the diverse EGFET devices will be presented, giving particular attention to the materials and technologies. MDPI 2018-11-20 /pmc/articles/PMC6263563/ /pubmed/30463318 http://dx.doi.org/10.3390/s18114042 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pullano, Salvatore Andrea Critello, Costantino Davide Mahbub, Ifana Tasneem, Nishat Tarannum Shamsir, Samira Islam, Syed Kamrul Greco, Marta Fiorillo, Antonino S. EGFET-Based Sensors for Bioanalytical Applications: A Review |
title | EGFET-Based Sensors for Bioanalytical Applications: A Review |
title_full | EGFET-Based Sensors for Bioanalytical Applications: A Review |
title_fullStr | EGFET-Based Sensors for Bioanalytical Applications: A Review |
title_full_unstemmed | EGFET-Based Sensors for Bioanalytical Applications: A Review |
title_short | EGFET-Based Sensors for Bioanalytical Applications: A Review |
title_sort | egfet-based sensors for bioanalytical applications: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263563/ https://www.ncbi.nlm.nih.gov/pubmed/30463318 http://dx.doi.org/10.3390/s18114042 |
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