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AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca(2+)-Permeable AMPA Receptors to Control LTP

Ca(2+)-permeable AMPA-type glutamate receptors (CP-AMPARs) containing GluA1 but lacking GluA2 subunits contribute to multiple forms of synaptic plasticity, including long-term potentiation (LTP), but mechanisms regulating CP-AMPARs are poorly understood. A-kinase anchoring protein (AKAP) 150 scaffol...

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Detalles Bibliográficos
Autores principales: Purkey, Alicia M., Woolfrey, Kevin M., Crosby, Kevin C., Stich, Dominik G., Chick, Wallace S., Aoto, Jason, Dell’Acqua, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263960/
https://www.ncbi.nlm.nih.gov/pubmed/30355502
http://dx.doi.org/10.1016/j.celrep.2018.09.085