Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes

A rational approach was used to synthesize a new set of 15 1H-1,2,4-triazol-3-yl benzenesulfonamide derivatives with the aim of developing new antimalarial lead compounds. These derivatives were prepared in yields between 50% and 62%, and their structures were elucidated using IR, (1)H-, (13)C-, (19...

Descripción completa

Detalles Bibliográficos
Autores principales: Boechat, Nubia, Pinheiro, Luiz C.S., Santos-Filho, Osvaldo A., Silva, Isabor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264137/
https://www.ncbi.nlm.nih.gov/pubmed/21934646
http://dx.doi.org/10.3390/molecules16098083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264137/
https://www.ncbi.nlm.nih.gov/pubmed/21934646
http://dx.doi.org/10.3390/molecules16098083

Ejemplares similares