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Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes
A rational approach was used to synthesize a new set of 15 1H-1,2,4-triazol-3-yl benzenesulfonamide derivatives with the aim of developing new antimalarial lead compounds. These derivatives were prepared in yields between 50% and 62%, and their structures were elucidated using IR, (1)H-, (13)C-, (19...
Autores principales: | Boechat, Nubia, Pinheiro, Luiz C.S., Santos-Filho, Osvaldo A., Silva, Isabor C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264137/ https://www.ncbi.nlm.nih.gov/pubmed/21934646 http://dx.doi.org/10.3390/molecules16098083 |
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