Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093

Four new pyridine derivatives, monasnicotinates A–D (1–4) were isolated from the red yeast rice of Monascus pilosus BCRC 38093. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Their inhibitory effe...

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Autores principales: Wu, Ming-Der, Cheng, Ming-Jen, Yech, Yi-Jen, Chen, Yen-Lin, Chen, Kai-Ping, Chen, Ih-Sheng, Yang, Ping-Hsun, Yuan, Gwo-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264138/
https://www.ncbi.nlm.nih.gov/pubmed/21654578
http://dx.doi.org/10.3390/molecules16064719
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author Wu, Ming-Der
Cheng, Ming-Jen
Yech, Yi-Jen
Chen, Yen-Lin
Chen, Kai-Ping
Chen, Ih-Sheng
Yang, Ping-Hsun
Yuan, Gwo-Fang
author_facet Wu, Ming-Der
Cheng, Ming-Jen
Yech, Yi-Jen
Chen, Yen-Lin
Chen, Kai-Ping
Chen, Ih-Sheng
Yang, Ping-Hsun
Yuan, Gwo-Fang
author_sort Wu, Ming-Der
collection PubMed
description Four new pyridine derivatives, monasnicotinates A–D (1–4) were isolated from the red yeast rice of Monascus pilosus BCRC 38093. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Their inhibitory effects on NO production was also evaluated.
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spelling pubmed-62641382018-12-10 Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093 Wu, Ming-Der Cheng, Ming-Jen Yech, Yi-Jen Chen, Yen-Lin Chen, Kai-Ping Chen, Ih-Sheng Yang, Ping-Hsun Yuan, Gwo-Fang Molecules Article Four new pyridine derivatives, monasnicotinates A–D (1–4) were isolated from the red yeast rice of Monascus pilosus BCRC 38093. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Their inhibitory effects on NO production was also evaluated. MDPI 2011-06-07 /pmc/articles/PMC6264138/ /pubmed/21654578 http://dx.doi.org/10.3390/molecules16064719 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wu, Ming-Der
Cheng, Ming-Jen
Yech, Yi-Jen
Chen, Yen-Lin
Chen, Kai-Ping
Chen, Ih-Sheng
Yang, Ping-Hsun
Yuan, Gwo-Fang
Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093
title Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093
title_full Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093
title_fullStr Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093
title_full_unstemmed Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093
title_short Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093
title_sort monasnicotinates a–d, four new pyridine alkaloids from the fungal strain monascus pilosus bcrc 38093
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264138/
https://www.ncbi.nlm.nih.gov/pubmed/21654578
http://dx.doi.org/10.3390/molecules16064719
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