Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction

Human myxovirus resistance 2 (MX2/MXB) is an interferon-induced post-entry inhibitor of human immunodeficiency virus type-1 (HIV-1) infection. While the precise mechanism of viral inhibition remains unclear, MX2 is localized to the nuclear envelope, and blocks the nuclear import of viral cDNAs. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Dicks, Matthew D. J., Betancor, Gilberto, Jimenez-Guardeño, Jose M., Pessel-Vivares, Lucie, Apolonia, Luis, Goujon, Caroline, Malim, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264145/
https://www.ncbi.nlm.nih.gov/pubmed/30496303
http://dx.doi.org/10.1371/journal.ppat.1007408

Ejemplares similares

Ejemplares similares