An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives

Reaction of allyl bromide (Z)-1 and (Z)-2 with N-substituted hydroxylamine hydrochlorides in presence of tert-butoxide in tert-butanol at reflux provides a short and effective route to [1,2]isoxazolidin-5-ones 3 and [1,2]oxazin-6-ones 4.

Detalles Bibliográficos
Autores principales: Beltaïef, Imen, Arfaoui, Aïcha, Amri, Hassen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264200/
https://www.ncbi.nlm.nih.gov/pubmed/20657429
http://dx.doi.org/10.3390/molecules15064094
_version_ 1783375441946476544
author Beltaïef, Imen
Arfaoui, Aïcha
Amri, Hassen
author_facet Beltaïef, Imen
Arfaoui, Aïcha
Amri, Hassen
author_sort Beltaïef, Imen
collection PubMed
description Reaction of allyl bromide (Z)-1 and (Z)-2 with N-substituted hydroxylamine hydrochlorides in presence of tert-butoxide in tert-butanol at reflux provides a short and effective route to [1,2]isoxazolidin-5-ones 3 and [1,2]oxazin-6-ones 4.
format Online
Article
Text
id pubmed-6264200
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62642002018-12-04 An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives Beltaïef, Imen Arfaoui, Aïcha Amri, Hassen Molecules Article Reaction of allyl bromide (Z)-1 and (Z)-2 with N-substituted hydroxylamine hydrochlorides in presence of tert-butoxide in tert-butanol at reflux provides a short and effective route to [1,2]isoxazolidin-5-ones 3 and [1,2]oxazin-6-ones 4. MDPI 2010-06-07 /pmc/articles/PMC6264200/ /pubmed/20657429 http://dx.doi.org/10.3390/molecules15064094 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Beltaïef, Imen
Arfaoui, Aïcha
Amri, Hassen
An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives
title An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives
title_full An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives
title_fullStr An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives
title_full_unstemmed An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives
title_short An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives
title_sort expeditious synthesis of [1,2]isoxazolidin-5-ones and [1,2]oxazin-6-ones from functional allyl bromide derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264200/
https://www.ncbi.nlm.nih.gov/pubmed/20657429
http://dx.doi.org/10.3390/molecules15064094
work_keys_str_mv AT beltaiefimen anexpeditioussynthesisof12isoxazolidin5onesand12oxazin6onesfromfunctionalallylbromidederivatives
AT arfaouiaicha anexpeditioussynthesisof12isoxazolidin5onesand12oxazin6onesfromfunctionalallylbromidederivatives
AT amrihassen anexpeditioussynthesisof12isoxazolidin5onesand12oxazin6onesfromfunctionalallylbromidederivatives
AT beltaiefimen expeditioussynthesisof12isoxazolidin5onesand12oxazin6onesfromfunctionalallylbromidederivatives
AT arfaouiaicha expeditioussynthesisof12isoxazolidin5onesand12oxazin6onesfromfunctionalallylbromidederivatives
AT amrihassen expeditioussynthesisof12isoxazolidin5onesand12oxazin6onesfromfunctionalallylbromidederivatives

Ejemplares similares