Cargando…
Generation and Detection of Levuglandins and Isolevuglandins In Vitro and In Vivo
Levuglandins (LGs) and isolevuglandins (isoLGs), formed by rearrangement of endoperoxide intermediates generated through the cyclooxygenase and free radical induced oxidation of polyunsaturated fatty acids (PUFAs), are extraordinarily reactive, forming covalent adducts incorporating protein lysyl ε-...
Autores principales: | Zhang, Ming, Li, Wei, Li, Tao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264246/ https://www.ncbi.nlm.nih.gov/pubmed/21705973 http://dx.doi.org/10.3390/molecules16075333 |
Ejemplares similares
-
Increased isolevuglandin-modified proteins in glaucomatous astrocytes
por: Govindarajan, Bharathi, et al.
Publicado: (2009) -
Targeting of reactive isolevuglandins in mitochondrial dysfunction and inflammation
por: Mayorov, Vladimir, et al.
Publicado: (2019) -
Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
por: Mont, Stacey, et al.
Publicado: (2016) -
The Adductomics of Isolevuglandins: Oxidation of IsoLG Pyrrole Intermediates Generates Pyrrole–Pyrrole Crosslinks and Lactams
por: Bi, Wenzhao, et al.
Publicado: (2019) -
Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension
por: Prinsen, Joseph K., et al.
Publicado: (2020)