1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives

A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivativeswith appropriate N-nucleophiles afforded the target compounds. All compounds were characterized by (1)H-, (13)C-NMR, GCMS, IR, and UV...

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Autores principales: Mabkhot, Yahia Nasser, Al-Majid, Abdullah Mohammed, Barakat, Assem, Alshahrani, Saeed, Siddiqui, Yamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264270/
https://www.ncbi.nlm.nih.gov/pubmed/21814162
http://dx.doi.org/10.3390/molecules16086502
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author Mabkhot, Yahia Nasser
Al-Majid, Abdullah Mohammed
Barakat, Assem
Alshahrani, Saeed
Siddiqui, Yamin
author_facet Mabkhot, Yahia Nasser
Al-Majid, Abdullah Mohammed
Barakat, Assem
Alshahrani, Saeed
Siddiqui, Yamin
author_sort Mabkhot, Yahia Nasser
collection PubMed
description A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivativeswith appropriate N-nucleophiles afforded the target compounds. All compounds were characterized by (1)H-, (13)C-NMR, GCMS, IR, and UV-Vis spectrometry. These compounds represent a new class of sulfur- and nitrogen-containing heterocycles that should also be of interest as new materials.
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spelling pubmed-62642702018-12-10 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives Mabkhot, Yahia Nasser Al-Majid, Abdullah Mohammed Barakat, Assem Alshahrani, Saeed Siddiqui, Yamin Molecules Article A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivativeswith appropriate N-nucleophiles afforded the target compounds. All compounds were characterized by (1)H-, (13)C-NMR, GCMS, IR, and UV-Vis spectrometry. These compounds represent a new class of sulfur- and nitrogen-containing heterocycles that should also be of interest as new materials. MDPI 2011-08-03 /pmc/articles/PMC6264270/ /pubmed/21814162 http://dx.doi.org/10.3390/molecules16086502 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Mabkhot, Yahia Nasser
Al-Majid, Abdullah Mohammed
Barakat, Assem
Alshahrani, Saeed
Siddiqui, Yamin
1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
title 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
title_full 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
title_fullStr 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
title_full_unstemmed 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
title_short 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives
title_sort 1,1’-(3-methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a building block in heterocyclic synthesis. novel synthesis of some pyrazole and pyrimidine derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264270/
https://www.ncbi.nlm.nih.gov/pubmed/21814162
http://dx.doi.org/10.3390/molecules16086502
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