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Enantioselective Evans-Tishchenko Reduction of β-Hydroxyketone Catalyzed by Lithium Binaphtholate

Lithium diphenylbinaphtholate catalyzed the enantioselective Evans-Tishchenko reduction of achiral β-hydroxyketones to afford monoacyl-protected 1,3-diols with high stereoselectivities. In the reaction of racemic β-hydroxyketones, kinetic optical resolution occurred in a highly stereoselective manne...

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Detalles Bibliográficos
Autores principales: Ichibakase, Tomonori, Nakatsu, Masato, Nakajima, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264331/
https://www.ncbi.nlm.nih.gov/pubmed/21694667
http://dx.doi.org/10.3390/molecules16065008