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Synthesis of Quinolin-2-one Alkaloid Derivatives and Their Inhibitory Activities against HIV-1 Reverse Transcriptase

Based on an established common pharmacophore of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNTTIs), a series of quinolin-2-one derivatives were synthesized and assayed for their in vitro activities against HIV-1 reverse transcriptase (RT) for the first time. Some of the tested compounds...

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Detalles Bibliográficos
Autores principales:	Cheng, Pi, Gu, Qiong, Liu, Wei, Zou, Jian-Feng, Ou, Yang-Yong, Luo, Zhong-Yong, Zeng, Jian-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264335/ https://www.ncbi.nlm.nih.gov/pubmed/21900867 http://dx.doi.org/10.3390/molecules16097649

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