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Synthesis and Contractile Activity of Substituted 1,2,3,4-Tetrahydroisoquinolines
A series of different 1-monosubstituted and 1,1-disubstituted 1,2,3,4-tetrahydro-isoquinolines was synthesized in high yields from different ketoamides. We have developed a convenient method for the synthesis of disubstituted derivatives by interaction of ketoamides with organomagnesium compounds, f...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264338/ https://www.ncbi.nlm.nih.gov/pubmed/21847072 http://dx.doi.org/10.3390/molecules16087019 |