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Synthesis and Contractile Activity of Substituted 1,2,3,4-Tetrahydroisoquinolines

A series of different 1-monosubstituted and 1,1-disubstituted 1,2,3,4-tetrahydro-isoquinolines was synthesized in high yields from different ketoamides. We have developed a convenient method for the synthesis of disubstituted derivatives by interaction of ketoamides with organomagnesium compounds, f...

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Detalles Bibliográficos
Autores principales: Ivanov, Iliyan, Nikolova, Stoyanka, Aladjov, Dimo, Stefanova, Iliyana, Zagorchev, Plamen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264338/
https://www.ncbi.nlm.nih.gov/pubmed/21847072
http://dx.doi.org/10.3390/molecules16087019