Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010

Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010. The assays were conducted mostly in vivo, and carrageenan-induced pedal e...

Descripción completa

Detalles Bibliográficos
Autores principales: Souto, Augusto Lopes, Tavares, Josean Fechine, da Silva, Marcelo Sobral, Diniz, Margareth de Fátima Formiga Melo, de Athayde-Filho, Petrônio Filgueiras, Filho, José Maria Barbosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264344/
https://www.ncbi.nlm.nih.gov/pubmed/21989312
http://dx.doi.org/10.3390/molecules16108515
_version_ 1783375474740690944
author Souto, Augusto Lopes
Tavares, Josean Fechine
da Silva, Marcelo Sobral
Diniz, Margareth de Fátima Formiga Melo
de Athayde-Filho, Petrônio Filgueiras
Filho, José Maria Barbosa
author_facet Souto, Augusto Lopes
Tavares, Josean Fechine
da Silva, Marcelo Sobral
Diniz, Margareth de Fátima Formiga Melo
de Athayde-Filho, Petrônio Filgueiras
Filho, José Maria Barbosa
author_sort Souto, Augusto Lopes
collection PubMed
description Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010. The assays were conducted mostly in vivo, and carrageenan-induced pedal edema was the most used experimental model. Of the 49 alkaloids evaluated, 40 demonstrated anti-inflammatory activity. Of these the most studied type were the isoquinolines. This review was based on NAPRALERT data bank, Web of Science and Chemical Abstracts. In this review, 95 references are cited.
format Online
Article
Text
id pubmed-6264344
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62643442018-12-10 Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010 Souto, Augusto Lopes Tavares, Josean Fechine da Silva, Marcelo Sobral Diniz, Margareth de Fátima Formiga Melo de Athayde-Filho, Petrônio Filgueiras Filho, José Maria Barbosa Molecules Review Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010. The assays were conducted mostly in vivo, and carrageenan-induced pedal edema was the most used experimental model. Of the 49 alkaloids evaluated, 40 demonstrated anti-inflammatory activity. Of these the most studied type were the isoquinolines. This review was based on NAPRALERT data bank, Web of Science and Chemical Abstracts. In this review, 95 references are cited. MDPI 2011-10-11 /pmc/articles/PMC6264344/ /pubmed/21989312 http://dx.doi.org/10.3390/molecules16108515 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Souto, Augusto Lopes
Tavares, Josean Fechine
da Silva, Marcelo Sobral
Diniz, Margareth de Fátima Formiga Melo
de Athayde-Filho, Petrônio Filgueiras
Filho, José Maria Barbosa
Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
title Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
title_full Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
title_fullStr Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
title_full_unstemmed Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
title_short Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010
title_sort anti-inflammatory activity of alkaloids: an update from 2000 to 2010
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264344/
https://www.ncbi.nlm.nih.gov/pubmed/21989312
http://dx.doi.org/10.3390/molecules16108515
work_keys_str_mv AT soutoaugustolopes antiinflammatoryactivityofalkaloidsanupdatefrom2000to2010
AT tavaresjoseanfechine antiinflammatoryactivityofalkaloidsanupdatefrom2000to2010
AT dasilvamarcelosobral antiinflammatoryactivityofalkaloidsanupdatefrom2000to2010
AT dinizmargarethdefatimaformigamelo antiinflammatoryactivityofalkaloidsanupdatefrom2000to2010
AT deathaydefilhopetroniofilgueiras antiinflammatoryactivityofalkaloidsanupdatefrom2000to2010
AT filhojosemariabarbosa antiinflammatoryactivityofalkaloidsanupdatefrom2000to2010

Ejemplares similares