Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo

Cell migration often involves the formation of sheet-like lamellipodia generated by branched actin filaments. The branches are initiated when Arp2/3 complex [1] is activated by WAVE regulatory complex (WRC) downstream of small GTPases of the Rac family [2]. Recent structural studies defined two inde...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaks, Matthias, Singh, Shashi P., Kage, Frieda, Thomason, Peter, Klünemann, Thomas, Steffen, Anika, Blankenfeldt, Wulf, Stradal, Theresia E., Insall, Robert H., Rottner, Klemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264382/
https://www.ncbi.nlm.nih.gov/pubmed/30393033
http://dx.doi.org/10.1016/j.cub.2018.10.002

Ejemplares similares

Ejemplares similares