Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds

Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a “low-temperature lipase-catalyzed transesterification” carried out at −40 °C.

Detalles Bibliográficos
Autores principales: Nakano, Toshiki, Yagi, Yusuke, Miyahara, Mizuki, Kaminura, Akio, Kawatsura, Motoi, Itoh, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264409/
https://www.ncbi.nlm.nih.gov/pubmed/21829150
http://dx.doi.org/10.3390/molecules16086747
Descripción
Sumario:Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a “low-temperature lipase-catalyzed transesterification” carried out at −40 °C.

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