Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds

Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a “low-temperature lipase-catalyzed transesterification” carried out at −40 °C.

Detalles Bibliográficos
Autores principales: Nakano, Toshiki, Yagi, Yusuke, Miyahara, Mizuki, Kaminura, Akio, Kawatsura, Motoi, Itoh, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264409/
https://www.ncbi.nlm.nih.gov/pubmed/21829150
http://dx.doi.org/10.3390/molecules16086747
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author Nakano, Toshiki
Yagi, Yusuke
Miyahara, Mizuki
Kaminura, Akio
Kawatsura, Motoi
Itoh, Toshiyuki
author_facet Nakano, Toshiki
Yagi, Yusuke
Miyahara, Mizuki
Kaminura, Akio
Kawatsura, Motoi
Itoh, Toshiyuki
author_sort Nakano, Toshiki
collection PubMed
description Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a “low-temperature lipase-catalyzed transesterification” carried out at −40 °C.
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spelling pubmed-62644092018-12-10 Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds Nakano, Toshiki Yagi, Yusuke Miyahara, Mizuki Kaminura, Akio Kawatsura, Motoi Itoh, Toshiyuki Molecules Article Optical resolution of 2-methyl-2-nitrobut-3-en-1-ol has been accomplished using a “low-temperature lipase-catalyzed transesterification” carried out at −40 °C. MDPI 2011-08-09 /pmc/articles/PMC6264409/ /pubmed/21829150 http://dx.doi.org/10.3390/molecules16086747 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Nakano, Toshiki
Yagi, Yusuke
Miyahara, Mizuki
Kaminura, Akio
Kawatsura, Motoi
Itoh, Toshiyuki
Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds
title Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds
title_full Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds
title_fullStr Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds
title_full_unstemmed Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds
title_short Chemo-Enzymatic Synthesis of a Multi-Useful Chiral Building Block Molecule for the Synthesis of Medicinal Compounds
title_sort chemo-enzymatic synthesis of a multi-useful chiral building block molecule for the synthesis of medicinal compounds
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264409/
https://www.ncbi.nlm.nih.gov/pubmed/21829150
http://dx.doi.org/10.3390/molecules16086747
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