In silico identification and experimental validation of hits active against KPC-2 β-lactamase

Bacterial resistance has become a worldwide concern, particularly after the emergence of resistant strains overproducing carbapenemases. Among these, the KPC-2 carbapenemase represents a significant clinical challenge, being characterized by a broad substrate spectrum that includes aminothiazoleoxim...

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Detalles Bibliográficos
Autores principales: Klein, Raphael, Linciano, Pasquale, Celenza, Giuseppe, Bellio, Pierangelo, Papaioannou, Sofia, Blazquez, Jesus, Cendron, Laura, Brenk, Ruth, Tondi, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264499/
https://www.ncbi.nlm.nih.gov/pubmed/30496182
http://dx.doi.org/10.1371/journal.pone.0203241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264499/
https://www.ncbi.nlm.nih.gov/pubmed/30496182
http://dx.doi.org/10.1371/journal.pone.0203241

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