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TargetClone: A multi-sample approach for reconstructing subclonal evolution of tumors

Most tumors are composed of a heterogeneous population of subclones. A more detailed insight into the subclonal evolution of these tumors can be helpful to study progression and treatment response. Problematically, tumor samples are typically very heterogeneous, making deconvolving individual tumor...

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Detalles Bibliográficos
Autores principales: Nieboer, Marleen M., Dorssers, Lambert C. J., Straver, Roy, Looijenga, Leendert H. J., de Ridder, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264523/
https://www.ncbi.nlm.nih.gov/pubmed/30496231
http://dx.doi.org/10.1371/journal.pone.0208002