Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System

A clean, practical and environmentally friendly synthesis in a homogeneous system has been developed for α-oxoketene S,S-acetals. A mixture of [Bmim]Cl and water was used as medium. The best economical and practical molar ratio of [Bmim]Cl to substrate was 4 to 1. With various types of 1,3-dicarbony...

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Detalles Bibliográficos
Autores principales: Yu, Ping, Zu, Yuangang, Fu, Yujie, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264552/
https://www.ncbi.nlm.nih.gov/pubmed/21623318
http://dx.doi.org/10.3390/molecules16064500
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author Yu, Ping
Zu, Yuangang
Fu, Yujie
Efferth, Thomas
author_facet Yu, Ping
Zu, Yuangang
Fu, Yujie
Efferth, Thomas
author_sort Yu, Ping
collection PubMed
description A clean, practical and environmentally friendly synthesis in a homogeneous system has been developed for α-oxoketene S,S-acetals. A mixture of [Bmim]Cl and water was used as medium. The best economical and practical molar ratio of [Bmim]Cl to substrate was 4 to 1. With various types of 1,3-dicarbonyl compounds as substrate, the corresponding α-oxoketene S,S-acetals have been prepared under mild reaction conditions with yields of 53–74% after purification with silica gel column. [Bmim]Cl/water can be recycled several times.
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spelling pubmed-62645522018-12-10 Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System Yu, Ping Zu, Yuangang Fu, Yujie Efferth, Thomas Molecules Article A clean, practical and environmentally friendly synthesis in a homogeneous system has been developed for α-oxoketene S,S-acetals. A mixture of [Bmim]Cl and water was used as medium. The best economical and practical molar ratio of [Bmim]Cl to substrate was 4 to 1. With various types of 1,3-dicarbonyl compounds as substrate, the corresponding α-oxoketene S,S-acetals have been prepared under mild reaction conditions with yields of 53–74% after purification with silica gel column. [Bmim]Cl/water can be recycled several times. MDPI 2011-05-27 /pmc/articles/PMC6264552/ /pubmed/21623318 http://dx.doi.org/10.3390/molecules16064500 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yu, Ping
Zu, Yuangang
Fu, Yujie
Efferth, Thomas
Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System
title Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System
title_full Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System
title_fullStr Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System
title_full_unstemmed Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System
title_short Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H(2)O Homogeneous System
title_sort catalytic synthesis of α-oxoketene s,s-acetals in a wet ionic liquid [bmim]cl/h(2)o homogeneous system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264552/
https://www.ncbi.nlm.nih.gov/pubmed/21623318
http://dx.doi.org/10.3390/molecules16064500
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AT fuyujie catalyticsynthesisofaoxoketenessacetalsinawetionicliquidbmimclh2ohomogeneoussystem
AT efferththomas catalyticsynthesisofaoxoketenessacetalsinawetionicliquidbmimclh2ohomogeneoussystem

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