Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems

In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALP...

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Autores principales: Wang, Yuefei, Bian, Xiaoying, Park, Jinhyouch, Ying, Le, Qian, Lisheng, Xu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264558/
https://www.ncbi.nlm.nih.gov/pubmed/21915094
http://dx.doi.org/10.3390/molecules16097762
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author Wang, Yuefei
Bian, Xiaoying
Park, Jinhyouch
Ying, Le
Qian, Lisheng
Xu, Ping
author_facet Wang, Yuefei
Bian, Xiaoying
Park, Jinhyouch
Ying, Le
Qian, Lisheng
Xu, Ping
author_sort Wang, Yuefei
collection PubMed
description In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALPS and ASPS were acid protein-bound heteropolysaccharides, although with considerably different chemical composition and molecular weight distribution. Meanwhile, in comparison with ALPS, ASPS exhibited stronger antioxidant activity and inhibitory potential against α-glucosidase according to the in vitro evaluation. Moreover, our results suggested that protein and uronic acid might, at least partly, contribute positively to the biological behavior of ALPS and ASPS.
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spelling pubmed-62645582018-12-10 Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems Wang, Yuefei Bian, Xiaoying Park, Jinhyouch Ying, Le Qian, Lisheng Xu, Ping Molecules Article In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALPS and ASPS were acid protein-bound heteropolysaccharides, although with considerably different chemical composition and molecular weight distribution. Meanwhile, in comparison with ALPS, ASPS exhibited stronger antioxidant activity and inhibitory potential against α-glucosidase according to the in vitro evaluation. Moreover, our results suggested that protein and uronic acid might, at least partly, contribute positively to the biological behavior of ALPS and ASPS. MDPI 2011-09-09 /pmc/articles/PMC6264558/ /pubmed/21915094 http://dx.doi.org/10.3390/molecules16097762 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Wang, Yuefei
Bian, Xiaoying
Park, Jinhyouch
Ying, Le
Qian, Lisheng
Xu, Ping
Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems
title Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems
title_full Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems
title_fullStr Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems
title_full_unstemmed Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems
title_short Physicochemical Properties, in Vitro Antioxidant Activities and Inhibitory Potential against α-Glucosidase of Polysaccharides from Ampelopsis grossedentata Leaves and Stems
title_sort physicochemical properties, in vitro antioxidant activities and inhibitory potential against α-glucosidase of polysaccharides from ampelopsis grossedentata leaves and stems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264558/
https://www.ncbi.nlm.nih.gov/pubmed/21915094
http://dx.doi.org/10.3390/molecules16097762
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