Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position

New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd(2)(dba)(3)/DPPF/Cs(2)CO(3)/toluene combination...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Gang, Zhang, Hao, Wang, Xiaojian, Li, Chun, Huang, Haihong, Yin, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264567/
https://www.ncbi.nlm.nih.gov/pubmed/21847070
http://dx.doi.org/10.3390/molecules16086985
_version_ 1783375527156908032
author Zhang, Gang
Zhang, Hao
Wang, Xiaojian
Li, Chun
Huang, Haihong
Yin, Dali
author_facet Zhang, Gang
Zhang, Hao
Wang, Xiaojian
Li, Chun
Huang, Haihong
Yin, Dali
author_sort Zhang, Gang
collection PubMed
description New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd(2)(dba)(3)/DPPF/Cs(2)CO(3)/toluene combination.
format Online
Article
Text
id pubmed-6264567
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62645672018-12-10 Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position Zhang, Gang Zhang, Hao Wang, Xiaojian Li, Chun Huang, Haihong Yin, Dali Molecules Article New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pd(2)(dba)(3)/DPPF/Cs(2)CO(3)/toluene combination. MDPI 2011-08-16 /pmc/articles/PMC6264567/ /pubmed/21847070 http://dx.doi.org/10.3390/molecules16086985 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zhang, Gang
Zhang, Hao
Wang, Xiaojian
Li, Chun
Huang, Haihong
Yin, Dali
Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_full Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_fullStr Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_full_unstemmed Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_short Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position
title_sort synthesis of new riminophenazines with pyrimidine and pyrazine substitution at the 2-n position
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264567/
https://www.ncbi.nlm.nih.gov/pubmed/21847070
http://dx.doi.org/10.3390/molecules16086985
work_keys_str_mv AT zhanggang synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT zhanghao synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT wangxiaojian synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT lichun synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT huanghaihong synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition
AT yindali synthesisofnewriminophenazineswithpyrimidineandpyrazinesubstitutionatthe2nposition

Ejemplares similares