Cargando…

Synthesis, Characterization, Acetylcholinesterase Inhibition, Molecular Modeling and Antioxidant Activities of Some Novel Schiff Bases Derived from 1-(2-Ketoiminoethyl)piperazines

Some novel Schiff bases derived from 1-(2-ketoiminoethyl)piperazines were synthesized and characterized by mass spectroscopy, FTIR, UV-Visible, (1)H and (13)C-NMR. The compounds were tested for inhibitory activities on human acetylcholinesterase (hAChE), antioxidant activities, acute oral toxicity a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salga, Saleh M., Ali, Hapipah M., Abdullah, Mahmood A., Abdelwahab, Siddig I., Wai, Lam Kok, Buckle, Michael J. C., Sukumaran, Sri Devi, Hadi, A. Hamid A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264571/ https://www.ncbi.nlm.nih.gov/pubmed/22064271 http://dx.doi.org/10.3390/molecules16119316

Ejemplares similares

Acute Oral Toxicity Evaluations of Some Zinc(II) Complexes Derived from 1-(2-Salicylaldiminoethyl)piperazine Schiff Bases in Rats
por: Salga, Muhammad Saleh, et al.
Publicado: (2012)

Mechanistic Studies of the Anti-Ulcerogenic Activity and Acute Toxicity Evaluation of Dichlorido-Copper(II)-4-(2-5-Bromo-benzylideneamino)ethyl) Piperazin-1-ium Phenolate Complex against Ethanol-Induced Gastric Injury in Rats
por: Salga, Muhammad Saleh, et al.
Publicado: (2011)

Synthesis, Characterization, X-ray Crystallography, Acetyl Cholinesterase Inhibition and Antioxidant Activities of Some Novel Ketone Derivatives of Gallic Hydrazide-Derived Schiff Bases
por: Gwaram, Nura Suleiman, et al.
Publicado: (2012)

4-(2-Azaniumylethyl)piperazin-1-ium bis(perchlorate)
por: Reisi, Mohammad Reza, et al.
Publicado: (2011)

Dichlorido(2-{[2-(piperazin-4-ium-1-yl)ethyl]iminomethyl}phenolate)cadmium(II)
por: Saleh Salga, Muhammad, et al.
Publicado: (2010)

Dichlorido(4-methoxy-2-{[2-(piperazin-4-ium-1-yl)ethyl]iminomethyl}phenolate)cadmium
por: Saleh Salga, Muhammad, et al.
Publicado: (2011)

Synthesis, Biological Evaluation and Molecular Modelling of 2′-Hydroxychalcones as Acetylcholinesterase Inhibitors
por: Sukumaran, Sri Devi, et al.
Publicado: (2016)

Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
por: Gwaram, Nura Suleiman, et al.
Publicado: (2012)

Analogues of 2′-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase
por: Sukumaran, Sri Devi, et al.
Publicado: (2020)

Virtual Screening and Biological Evaluation of Piperazine Derivatives as Human Acetylcholinesterase Inhibitors
por: Varadaraju, Kavitha Raj, et al.
Publicado: (2013)

Apoptotic effect of novel Schiff Based CdCl(2)(C(14)H(21)N(3)O(2)) complex is mediated via activation of the mitochondrial pathway in colon cancer cells
por: Hajrezaie, Maryam, et al.
Publicado: (2015)

Corrigendum: Apoptotic effect of novel Schiff Based CdCl(2)(C(14)H(21)N(3)O(2)) complex is mediated via activation of the mitochondrial pathway in colon cancer cells
por: Hajrezaie, Maryam, et al.
Publicado: (2017)

Chemoprevention of Colonic Aberrant Crypt Foci by Novel Schiff Based Dichlorido(4-Methoxy-2-{[2-(Piperazin-4-Ium-1-Yl)Ethyl]Iminomethyl}Phenolate)Cd Complex in Azoxymethane-Induced Colorectal Cancer in Rats
por: Hajrezaie, Maryam, et al.
Publicado: (2015)

(1R,2R)-N,N′-Bis[1-(2-pyridyl)ethylidene]cyclohexane-1,2-diamine
por: Saleh Salga, Muhammad, et al.
Publicado: (2010)

Dichlorido{N,N-dimethyl-N′-[1-(2-pyridyl)ethylidene]ethane-1,2-diamine-κ(3) N,N′,N′′}copper(II)
por: Saleh Salga, Muhammad, et al.
Publicado: (2010)

Gastroprotection Studies of Schiff Base Zinc (II) Derivative Complex against Acute Superficial Hemorrhagic Mucosal Lesions in Rats
por: Golbabapour, Shahram, et al.
Publicado: (2013)

Acute Toxicity and Gastroprotection Studies of a New Schiff Base Derived Copper (II) Complex against Ethanol-Induced Acute Gastric Lesions in Rats
por: Hajrezaie, Maryam, et al.
Publicado: (2012)

Screening for antimalarial and acetylcholinesterase inhibitory activities of some Iranian seaweeds
por: Ghannadi, A, et al.
Publicado: (2013)

Stability monitoring of some acetylcholinesterase reactivating drugs
por: Ram, Nazila, et al.
Publicado: (2011)

Discovery of Novel Coumarin-Schiff Base Hybrids as Potential Acetylcholinesterase Inhibitors: Design, Synthesis, Enzyme Inhibition, and Computational Studies
por: Hasan, Aso Hameed, et al.
Publicado: (2023)

Benzimidazole–Piperazine–Coumarin/Cucurbit[7]uril Supramolecular Photoinduced Electron Transfer Fluorochromes for Detection of Carnosol by Stimuli-Responsive Dye Displacement and pK(a) Tuning
por: Bojesomo, Rukayat S., et al.
Publicado: (2022)

Synthesis, Structural, and Biological Studies of Some Schiff Bases and Their Metal Complexes
por: Mishra, A. P., et al.
Publicado: (2008)

2-Aryl-3-(arylideneamino)-1,2-dihydroquinazoline-4(3H)-ones as inhibitors of cholinesterases and self-induced β-amyloid (Aβ) aggregation: biological evaluations and mechanistic insights from molecular dynamics simulations
por: Sukumaran, Sri Devi, et al.
Publicado: (2018)

Synthesis, Characterization and Biocidal Activities of Some Schiff Base Metal Complexes
por: Neelakantan, M. A., et al.
Publicado: (2010)

Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
por: Azab, Mohamed E., et al.
Publicado: (2015)

Screening the methanol extracts of some Iranian plants for acetylcholinesterase inhibitory activity
por: Gholamhoseinian, A., et al.
Publicado: (2009)

New 3-O-substituted xanthone derivatives as promising acetylcholinesterase inhibitors
por: Loh, Zi Han, et al.
Publicado: (2021)

Synthesis and Biological Activity of Some 3-(4-(Substituted)-piperazin-1-yl)cinnolines
por: Awad, Eman D., et al.
Publicado: (2011)

On Some Structural Analogies between Acetylcholinesterase and the Macromolecular Receptor of Acetylcholine
por: Changeux, Jean-Pierre, et al.
Publicado: (1969)

Acute Toxicity and Gastroprotective Effect of the Schiff Base Ligand 1H-Indole-3-ethylene-5-nitrosalicylaldimine and Its Nickel (II) Complex on Ethanol Induced Gastric Lesions in Rats
por: Ibrahim, Mohamed Mustafa, et al.
Publicado: (2012)

Synthesis and Anti-Bacterial Activities of Some Novel Schiff Bases Derived from Aminophenazone
por: Asiri, Abdullah M., et al.
Publicado: (2010)

In Silico and In Vitro Analysis of Bacoside A Aglycones and Its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri
por: Ramasamy, Seetha, et al.
Publicado: (2015)

Synthesis, crystal structures, Hirshfeld surface analysis and spectroscopic studies of two Schiff bases of anisaldehyde and their urease and acetylcholinesterase inhibitory and antioxidant properties
por: Muhammad, Amber Jan, et al.
Publicado: (2019)

Hexachloridobis{μ(2)-2-(piperazin-1-yl)-N-[1-(2-pyridyl)ethylidene]ethanamine}trizinc dihydrate
por: Suleiman Gwaram, Nura, et al.
Publicado: (2011)

Antibacterial and Antifungal Studies on Some Schiff Base Complexes of Zinc(II)
por: Joseyphus, R. Selwin, et al.
Publicado: (2008)

Structure-Activity Relationships for Some Diamine, Triamine and Schiff Base Derivatives and Their Copper(II) Complexes
por: Bolos, C. A., et al.
Publicado: (1998)

2-{[2-(Piperazin-4-ium-1-yl)ethyliminio]methyl}phenolate 0.06-chloride 0.94-perchlorate
por: Reisi, Mohammad Reza, et al.
Publicado: (2011)

Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity
por: Yücel, Nazlı Turan, et al.
Publicado: (2021)

Tautomerism and antioxidant activity of some 4-acylpyrazolone-based Schiff bases: a theoretical study
por: Orabi, Esam A.
Publicado: (2018)

Ipomoea aquatica Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity
por: Alkiyumi, Salim Said, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6etavkvhqa6jmocpk4pn6an75v